Acyl bromides
Medchemexpress LLC Cimetropium Bromide | 51598-60-8 | 438.36 | 10 MG
Cimetropium Bromide (DA-3177) is a muscarinic acetylcholine receptor (mAChR) antagonist used for the long-term treatment of irritable bowel syndrome. It is a competitive antagonist of muscarinic-mediated contractions in isolated colonic preparations. In vivo, it acts as a potent inhibitor of large bowel motility.
- Used for long-term treatment of irritable bowel syndrome
- Competitive antagonist of muscarinic-mediated contractions
- Potent antimuscarinic effect in inhibiting longitudinal muscle contraction
- Potent inhibitor of large bowel motility evoked by exogenous and endogenous stimuli
Medchemexpress LLC KRN2 bromide | 1390654-28-0 | 98.8% | 524.38 | 25 MG
KRN2 bromide is a selective inhibitor of nuclear factor of activated T cells (NFAT5), with an IC50 of 0.1 μM. It selectively suppresses the expression of pro-inflammatory genes, including Nos2 and Il6. It also dose-dependently inhibits NF-κB p65 binding to Nfat5 promoter 1 and directly blocks the interaction between NF-κB p65 and its DNA binding sequence.
- Selectively inhibits nuclear factor of activated T cells (NFAT5).
- Suppresses expression of pro-inflammatory genes.
- Inhibits NF-κB p65 binding to Nfat5 promoter.
- Effectively suppresses AIA and CIA in mice, decreasing pro-inflammatory cytokines and autoantibodies.
Medchemexpress LLC Biotin-PEG3-bromide | 1041766-91-9 | 95.0% | 482.43 g·mol⁻1 | C18H32BrN3O5S | 25 MG
Biotin-PEG3-bromide is a biotinylated short polyethylene glycol (PEG3) linker with a terminal alkyl bromide. It is used to introduce a biotin affinity tag onto molecules via nucleophilic substitution or cross-coupling reactions, enabling streptavidin-based capture, detection, and pull-down workflows in chemical biology and bioconjugation studies.
- Reactive alkyl bromide suitable for nucleophilic substitution and cross-coupling reactions.
- Biotin moiety enables high-affinity capture with streptavidin/avidin reagents.
- Short PEG3 spacer improves solubility and reduces steric hindrance.
- High solubility in DMSO allows preparation of concentrated stock solutions.
- Powder stable at -20°C; follow recommended storage for solutions to maintain integrity.
Medchemexpress LLC Aclidinium bromide | 320345-99-1 | MFCD22683690 | 99.0% | C26H30BrNO4S2 | 10MG
Aclidinium bromide is a long-acting inhaled muscarinic antagonist used in respiratory research, primarily for studies of chronic obstructive pulmonary disease (COPD) and muscarinic receptor function. Supplied as the bromide salt with characterized identity and high purity, it is intended for in vitro and preclinical pharmacology applications.
- Long-acting muscarinic antagonist for COPD and airway research.
- High purity suitable for analytical and pharmacological studies.
- Available as solid and DMSO solution formats for flexible use.
- Well-characterized chemical identity and molecular data.
- Useful as a pharmacological tool to probe muscarinic receptor-mediated bronchodilation.
Medchemexpress LLC N6-Benzoyl-5′-O-(4,4′-dimethoxytrityl)-2′-deoxyadenosine | 64325-78-6 | 98.0% | 657.71 | 10 G
N6-Benzoyl-5′-O-(4,4′-dimethoxytrityl)-2′-deoxyadenosine can be used as an intermediate. It is for research use only and not sold to patients. The product appears as a white to off-white solid.
- Used as an intermediate.
- Solid appearance.
- White to off-white color.
- Available for research purposes.
Medchemexpress LLC 1,3,5-Tri-o-benzoyl-a-d-ribofuranose | 22224-41-5 | 99.75% | 462.45 | 1 ML
1,3,5-Tri-O-benzoyl-a-D-ribofuranose is a purine nucleoside analog, which exhibits broad antitumor activity by targeting indolent lymphoid malignancies. Its anticancer mechanisms involve inhibiting DNA synthesis and inducing apoptosis.
- Purine nucleoside analog
- Broad antitumor activity
- Targets indolent lymphoid malignancies
- Inhibits DNA synthesis
- Induces apoptosis
Selleck Chemical LLC Sepantronium Bromide (YM155) S1130-1g
Sepantronium Bromide(YM155) is a potent survivin suppressant by inhibiting Survivin promoter activity with IC50 of 0 54 nM in HeLa-SURP-luc and CHO-SV40-luc cells does not significantly inhibit SV40 promoter activity but is observed to slightly inhibit the interaction of Survivin with XIAP YM155 down-regulates survivin and XIAP modulates autophagy and induces autophagy-dependent DNA damage in breast cancer cells Phase 2
Cayman Chemical p-Benzoyl-L-phenylalnIn 5g
A photoreactive derivative of L-phenylalanine; can be incorporated into synthetic peptides and used as a photolabel to identify the residues involved in peptide-protein interactions; has been incorporated into GPCRs to identify potential ligand binding sites
Medchemexpress LLC Thonzonium bromide | 553-08-2 | 99.86% | 1 ML
Thonzonium bromide is an antibacterial agent and monocationic surface-active agent that inhibits RANKL-induced osteoclast formation and bone resorption in vitro. It prevents LPS-induced bone loss in vivo by blocking RANKL-induced activation of NF-κB, ERK, c-Fos, and NFATc1, which are crucial for osteoclast formation. Additionally, it disrupts F-actin ring formation in mature osteoclasts and inhibits proton transport in a dose-dependent manner.
- Inhibits RANKL-induced osteoclast formation
- Prevents LPS-induced bone loss in vivo
- Blocks key signaling pathways for osteoclast formation
- Disrupts F-actin ring formation in mature osteoclasts
- Inhibits proton transport
Medchemexpress LLC Tiotropium bromide monohydrate | 411207-31-3 | 99.7% | 100 MG
Tiotropium bromide (BA-679 BR) monohydrate is a long-acting muscarinic receptor antagonist. It is for research use only.
- Long-acting muscarinic receptor antagonist.
Medchemexpress LLC Cetrimonium (bromide) | 57-09-0 | 1 G
Cetrimonium bromide (CTAB) is an orally active cationic surfactant and a quaternary ammonium compound. It exhibits toxicity and anticancer effects, inhibiting cell migration and invasion by modulating canonical and non-canonical TGF-β signaling pathways. It can also be utilized for DNA extraction.
- Cationic surfactant
- Quaternary ammonium compound
- Inhibits cell migration and invasion
- Modulates TGF-β signaling pathways
- Used for DNA extraction
- Has toxicity and anticancer effects
Cayman Chemical N4-benzoyl-2-DeoxycytIdIn 10g
A building block; has been used in the synthesis of nucleosides and nucleotides with anticancer activity, as well as oligonucleotides
Medchemexpress LLC Demecarium bromide | 56-94-0 | 95.0% | 100 MG
Demecarium Bromide is a potent cholinesterase inhibitor, with an apparent affinity (Kiapp) of 0.15 μM. It is used as a glaucoma agent.
- Potent cholinesterase inhibitor
- Used as a glaucoma agent
- Purity of 95.0%
- Stable under recommended storage conditions
- Solid appearance
Medchemexpress LLC Pinaverium bromide | 53251-94-8 | MFCD08063574 | 98.0% | 591.42 g/mol | C26H41Br2NO4 | 5 MG
Pinaverium bromide is an analytical research standard of an L-type calcium channel blocker with selectivity for the gastrointestinal tract. Supplied in small laboratory pack sizes, it is intended for analytical and pharmacological research, method development, and use as a reference material. The compound has formula C26H41Br2NO4, molecular weight 591.42 g/mol, and CAS 53251-94-8.
- Research-grade analytical standard for L-type calcium channel studies.
- Supplied in small, lab-friendly pack sizes for routine use.
- High purity suitable for analytical and pharmacological assays.
- Datasheet, safety data sheet, and certificate of analysis available on request.
- Stable bromide salt form appropriate for gastrointestinal pharmacology research.
AdipoGen Dimidium bromide
Chemical. CAS 518-67-2. Formula C20H18BrN3. MW 380.28. Synthetic. Intercalating probe for nucleic acids. Other applications include the determination of cationic surfactants.